Assistant Laboratory Animal Technician (ALAT) Practice Exam

Which principle focuses on minimizing the number of animals used in research?

1. Refinement

2. Reduction

3. Replacement

4. Regulation

The correct answer is: Reduction

The principle that focuses on minimizing the number of animals used in research is known as Reduction. This principle emphasizes the importance of designing research studies in a way that carefully considers the number of animals needed to achieve valid results. By employing strategies such as using statistical methods to ensure that the fewest animals necessary are utilized or enhancing experimental design to maximize the information gained from fewer subjects, researchers can adhere to ethical standards while still obtaining valuable scientific data. This approach not only conserves animal life but also aligns with ethical considerations within scientific research, making it a critical component of responsible animal use in experiments. In contrast to Reduction, the other principles serve different purposes in the ethical framework of animal research. Refinement refers to modifying procedures to minimize pain and distress, Replacement involves using alternative methods that do not involve animals, and Regulation pertains to the set of rules and guidelines that oversee the care and use of laboratory animals. Each principle plays an important role in promoting ethical practices, but Reduction specifically targets the minimization of the animal population used in research efforts.