Assistant Laboratory Animal Technician (ALAT) Practice Exam

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What are hybrid mice?

  1. Offspring of two different strains of mice

  2. Strains with mixed genetic heritage

  3. Mice that are laboratory breeds

  4. Mice with genetic mutations

The correct answer is: Offspring of two different strains of mice

Hybrid mice refer specifically to the offspring produced from the mating of two different strains of mice. This hybridization often occurs to leverage desirable traits from both parental strains, which may include variations in phenotype, behavior, or genetic characteristics. Researchers may create hybrids for various purposes in scientific studies, such as understanding genetic diseases, testing therapies, or studying specific biological phenomena. In contrast, strains with mixed genetic heritage suggest a broader genetic background without necessarily implying that they are first-generation hybrids. Laboratory breeds and genetically mutated mice might have specific traits or characteristics but do not specifically define the term "hybrid" in the context of resulting offspring from different strains. Therefore, the essence of hybrid mice lies in their direct origin from distinct genetic lines, making the identification of them as offspring of different strains the most accurate description.